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The Center for Research Informatics (CRI) at the University of Illinois-Chicago (UIC) provides advanced computing and statistical expertise to support the analytic activities related to genetics, genomics, transcriptomics, epigenomics, proteomics, translational informatics, and clinical informatics for the UIC and Chicago-area research community. The center also focuses on providing infrastructure, data management, computation, high performance computing, domain expertise and analytical services, as well as supporting and coordinating inter-disciplinary research initiatives. CRI aids researchers with the management, integration, and contextual analysis of data, provides training on tools, databases, and best practices, and supports grant activities.

Statistical analysis for high-throughput experiments includes SNP genotyping, SNP detection by DNA sequencing, gene expression analysis from microarray or RNA-seq, ChIP-seq, gene methylation, and single-cell studies. Continued support is provided to researchers by designing, customizing, and implementing analyses necessary for a systems-level biological understanding. Such projects may include integration of multiple types of -omics data, associations of genetic data with phenotypes or other clinical data (i.e., case/control studies), development of novel pipelines. Additionally, the CRI advises on experimental design to optimize the use of often-limited experimental resources, creates data visualizations (e.g., heat maps, NMDS plots, etc.), and assists with manuscript and grant writing/preparation.

Additionally, CRI provides clinical information services to the UIC community and other organizations, including but not limited to patient data analysis, cohort identification for clinical trials (UIC i2b2 server), and clinical data warehousing. In collaboration with the UIC Center for Clinical and Translational Science (CCTS), CRI extracts and analyzes data from data warehouses and other clinical data sources at UIC for research, builds relevant data-marts, and supports the UI Biorepository. Support is also provided for the data, research, and analytics associated with Medicaid, Medicare, and Public Health databases. Furthermore, CRI offers support and expertise related to medical coding, medical terminologies, health information systems, revenue cycle/billing, and process and quality improvement. CRI’s aim is to aid investigators and clinicians in their medical research and clinical trials while offering distinctive know-how in health informatics.

Managed by the Research Resources Center (RRC), the center is funded by the Office of the Vice-Chancellor for Research (OVCR) and supported in part by the Cancer Center (UICC), the Center for Clinical and Translational Science (CCTS), and by various colleges and departments.




  • Click here to learn how to create a RRC User Account and a RRCAN.
  • Click here to fill out a Service Request Form.
  • If you submit a service request form, please ALSO contact us via email to set up a consultation.