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While genetic variation measures the changes in the information encoded in the genome, gene expression measures how that information is used. RNA-seq has fast become the standard platform for transcriptomic measurements, providing a wide dynamic range of expression levels that is extendable to the analysis of non-coding transcripts and gene isoforms, and to miRNAs. The CRI provides analysis support for numerous transcriptomics experiments, including:

  • Identification of differentially expressed genes or miRNAs
  • Identification of differentially expressed gene isoforms, or alternative splicing
  • RNA editing
  • Allelic expression
  • RNA fusion